| Assay ID | Title | Year | Journal | Article |
|---|
| AID425683 | Inhibition of PDE4A1A | 2009 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 19, Issue:13
| Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors. |
| AID425879 | Intrinsic clearance in rat microsomes | 2009 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 19, Issue:13
| Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors. |
| AID425687 | Inhibition of PDE4D2 | 2009 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 19, Issue:13
| Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors. |
| AID425876 | Inhibition of PDE7A at 10 uM | 2009 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 19, Issue:13
| Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors. |
| AID425692 | Inhibition of PDE9A2 | 2009 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 19, Issue:13
| Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors. |
| AID425684 | Inhibition of PDE4B1 | 2009 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 19, Issue:13
| Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors. |
| AID425681 | Inhibition of PDE3A | 2009 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 19, Issue:13
| Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors. |
| AID425872 | Inhibition of PDE2A at 10 uM | 2009 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 19, Issue:13
| Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors. |
| AID425686 | Inhibition of PDE4C1 | 2009 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 19, Issue:13
| Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors. |
| AID425677 | Inhibition of PDE1A | 2009 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 19, Issue:13
| Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors. |
| AID425675 | Inhibition of PDE10A1 | 2009 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 19, Issue:13
| Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors. |
| AID425676 | Inhibition of human PDE4A by IMAP fluorescence polarization technology | 2009 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 19, Issue:13
| Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors. |
| AID425880 | Metabolic stability in rat assessed as half life | 2009 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 19, Issue:13
| Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors. |
| AID425682 | Inhibition of PDE3B | 2009 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 19, Issue:13
| Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors. |
| AID425878 | Inhibition of PDE8A1 at 10 uM | 2009 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 19, Issue:13
| Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors. |
| AID425694 | Inhibition of PDE4 expressed in HEK293 cells coexpressing G-protein coupled receptor and cyclic nucleotide gated ion channel by fluorescence assay | 2009 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 19, Issue:13
| Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors. |
| AID425871 | Inhibition of PDE1C at 10 uM | 2009 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 19, Issue:13
| Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors. |
| AID314433 | Inhibition of human PDE4A1A by IMAP technology | 2008 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 18, Issue:4
| Identification of a potent new chemotype for the selective inhibition of PDE4. |
| AID425875 | Inhibition of PDE5A1 at 10 uM | 2009 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 19, Issue:13
| Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors. |
| AID425693 | Inhibition of PDE11A4 | 2009 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 19, Issue:13
| Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors. |
| AID425685 | Inhibition of PDE4B2 | 2009 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 19, Issue:13
| Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors. |
| AID425877 | Inhibition of PDE7B at 10 uM | 2009 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 19, Issue:13
| Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors. |
| AID425678 | Inhibition of PDE1B | 2009 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 19, Issue:13
| Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors. |
| AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | | | |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID504812 | Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID504810 | Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID1745845 | Primary qHTS for Inhibitors of ATXN expression | | | |
| AID1799059 | PDE4A Inhibition Assay from Article 10.1016/j.bmcl.2009.01.057: \\Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors.\\ | 2009 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 19, Issue:13
| Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors. |
| AID1799060 | PDE4A Inhibition Assay from Article 10.1016/j.bmcl.2008.01.028: \\Identification of a potent new chemotype for the selective inhibition of PDE4.\\ | 2008 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 18, Issue:4
| Identification of a potent new chemotype for the selective inhibition of PDE4. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |